Ebola Vaccine Trials Under Way in Mali

October 11th, 2014

Mmm hmm.

Via: Guardian:

Health workers in Mali have been given an experimental vaccine against Ebola designed to boost the immunity of those on the frontline of the battle against the disease, which has so far claimed more than 3,800 lives in west Africa.

Mali has no Ebola cases but it borders Guinea, where the outbreak began. The trials are taking place to determine whether the potential vaccine is safe and that it does at least have some sort of protective effect.

It is particularly important to test its effects on health workers, who in Guinea, Sierra Leone and Liberia are at the sharp end of the battle against the virus.

Safety trials began at Oxford University and in the US a couple of weeks ago. The healthy people who volunteered have so far shown no ill effects, so the trials have moved into Africa itself.

“This research will give us crucial information about whether the vaccine is safe, well-tolerated and capable of stimulating adequate immune responses in the highest priority target population – healthcare workers in west Africa,” said Prof Myron Levine, director of the centre for vaccine development at the University of Maryland, which is running the trial in conjunction with the Malian ministry of health.

“If it works, in the foreseeable future it could help alter the dynamic of this epidemic by interrupting transmission to healthcare and other exposed frontline workers.”

At this point, the researchers hope to establish that there are no significant ill effects, beyond perhaps a temporarily sore arm. But they will also be testing blood samples of the volunteers to ensure there is an antibody response, which is the signal that the vaccine may teach the immune system to recognise the virus and fight it off. Until it is used in health workers treating people with Ebola, however, there will be no real proof that it works.

The trials are proceeding with unprecedented speed with the cooperation of a large number of international organisations and governments, in the hope of having something available that is at least partially protective before the end of the year.

One Response to “Ebola Vaccine Trials Under Way in Mali”

  1. dale says:

    Mali has no Ebola cases but…
    Health workers in Mali have been given an experimental vaccine…

    Mali. I didn’t see that coming, and now I’m aking myself, “why not?”

    Au, don’t tell me there’s no hope at all, divided we stand, together we fall.

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