DARPA Is Making Insects That Can Deliver Bioweapons

October 4th, 2018

You’ll love this one.

Via: Newsweek:

The U.S. government’s Defense Advanced Research Projects Agency (DARPA) has been accused of trying to create a new class of biological weapons that would be delivered via virus-infected insects.

The Insect Allies program was announced by DARPA in 2016. It is a research project that aims to protect the U.S. agricultural food supply by delivering protective genes to plants via insects, which are responsible for the transmission of most plant viruses. Scientists believe loading the bugs up with viruses that would offer plants protective benefits could be one way of ensuring food security in the event of a major threat.

In an editorial published in the journal Science, a group of researchers led by Richard Guy Reeves, from the Max Planck Institute for Evolutionary Biology in Germany, says Insect Allies isn’t exactly what it says it is. Instead, they claim DARPA is potentially developing insects as a means of delivering a “new class of biological weapon.”

Genetically altering a species to make it more resilient comes with problems. Introducing alterations directly into a species’ chromosome is slow, as the alteration must be passed down through generations before it takes hold.

Instead, scientists with DARPA are looking at introducing genetically modified viruses that can edit chromosomes directly in fields—these are known as horizontal environmental genetic alteration agents (HEGAAs).

The DARPA program is using the principles of HEGAAs but, unlike traditional methods of dispersal—like spraying fields with them—it wants to spread them through insects. At the moment, maize and tomato plants are being used in experiments and the insects being used for dispersal are leafhoppers, aphids and whiteflies.

“Insect Allies aims to develop scalable, readily deployable, and generalizable countermeasures against potential natural and engineered threats to mature crops,” Blake Bextine, DARPA Program Manager for Insect Allies, told Newsweek. “The program is devising technologies to engineer and deliver these targeted therapies on relevant timescales—that is, within a single growing season. To do so, Insect Allies researchers are building on natural, efficient, and highly specific plant virus and insect vector delivery systems to transfer modified, protective genes to plants.”
Why Biological Weapons?

Reeves and his colleagues offer a number of assertions about why Insect Allies could end up being a means of bioweapon dispersal. Firstly, they question the very nature of the project—the use of insects. Why, they say, are insects so integral? What is the problem with spraying HEGAAs?

The team says Insect Allies “appears very limited in its capacity to enhance U.S. agriculture or respond to national emergencies…. As a result, the program may be widely perceived as an effort to develop biological agents for hostile purposes and their means of delivery.”

Potentially, the viruses being introduced could do harm instead of good. The insects could be used to disperse agents that would prevent seeds from growing. “HEGAA weapons could be extremely transmissible to susceptible crop species, particularly where insects were used as the means of delivery,” they write. “Chromosomal editing would be targetable to particular crop varieties dependent on their genome sequence (presumably those varieties not grown by the deploying parties).”

The development of an insect-based system, according to the authors, points to “an intention to develop a means of delivery of HEGAAs for offensive purposes.” The technology, they say, could quickly be simplified and used to develop a whole new class of biological weapons. “In our view, the program is primarily a bad idea because obvious simplifications of the work plan with already-existing technology can generate predictable and fast-acting weapons, along with their means of delivery, capable of threatening virtually any crop species,” they wrote.

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