Sperm Sorting Method Could Reduce Chances of Girls Being Born, Scientists Warn

August 16th, 2019

“Like most Asian nations, China has a traditional bias for sons.”

Via: New Scientist:

The finding that some chemicals slow down sperm that carry the X chromosome could lead to gels for home use that make a couple less likely to conceive a girl, scientists have warned.

“I am concerned about the social impact of this,” says Alireza Fazeli of Tartu University in Estonia. “It’s so simple. You could start to do it in your bedroom. Nobody would be able to stop you from doing it.”

It was thought that the sperm of mammals that lead to male and female offspring are identical except for the DNA they carry. But Masayuki Shimada of Hiroshima University in Japan and his colleagues have found that 500 genes are active in sperm that carry the X chromosome, which give rise to female offspring, that aren’t active in sperm that carry the Y chromosome, which lead to male offspring.

Of these genes, 18 code for proteins that stick out from the sperm cell’s surface. The team has found that chemicals that bind to two of these proteins can slow down the movement of X-carrying sperm without affecting the Y-carrying ones.

This discovery makes it simple to separate sperm according to the sex of the offspring they could produce. When the researchers used this method on mouse sperm, they found that selecting the fastest swimmers for conception led to 90 per cent of the resulting pups being male. When they used slowed-down sperm, the pups were 81 per cent female.

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