“Several Vaccines Will Likely Be Needed To Combat The Coronavirus”

May 12th, 2020

haha Tell me another one.

Via: Bloomberg:

Several vaccines will likely be needed to combat the coronavirus and immunize groups of people in America and abroad, U.S. National Institutes of Health Director Francis Collins said in an interview.

8 Responses to ““Several Vaccines Will Likely Be Needed To Combat The Coronavirus””

  1. Dennis says:

    I did a quick search to see where Collins and Bill popped up together and found this intriguing sentence:

    “The potential beauty of in vivo gene editing is that it might be given ultimately as a single shot, curing everyone in a scalable manner”

    https://www.sciencemag.org/news/2019/10/nih-and-gates-foundation-lay-out-ambitious-plan-bring-gene-based-treatments-hiv-and

  2. Dennis says:

    And this one:

    Another “very promising area” of intramural research is viral-based vaccine constructs that convert host cells into “a factory” of disease-fighting antibodies, enabling “protection more rapidly than natural immunity,” Gates said.

    https://irp.nih.gov/catalyst/v22i1/bill-gates-asks-nih-scientists-for-help-in-saving-lives

  3. NH says:

    @ Dennis—it has gotten much worse. Many of these new vaccines cause the “citizen’s” cells to produce the antigen itself, which is then responded to by the immune system.

    https://childrenshealthdefense.org/news/vaccine-safety/covid-19-the-spearpoint-for-rolling-out-a-new-era-of-high-risk-genetically-engineered-vaccines/

    “Desirous of streamlining vaccine technology still further and enabling vaccine stockpiles in an even shorter time frame, researchers began tinkering in the mid-1990s with nucleic acid vaccines, which include DNA vaccines and messenger RNA (mRNA) vaccines. As a form of gene therapy, both represent a significant departure from classical vaccines. Whereas the latter introduce a vaccine antigen to produce an immune response, nucleic acid vaccines instead send the body instructions to produce the antigen itself. As one researcher explains, the nucleic acids “cause the cells to make pieces of the virus,” with the goal being that the immune system then “mounts a response to those pieces of the virus.”
    Researchers quickly learned that both the DNA and mRNA vaccine options have serious downsides, and as a result, vaccines of this type have never been licensed. Nonetheless, almost one-fourth (20/83) of the vaccines listed by the World Health Organization as COVID-19 “candidate vaccines” as of April 23—including two of the leading contenders—are DNA (Inovio) or mRNA (Moderna) vaccines (see table).”
    “A second aspect of DNA vaccines—their gene-altering properties—is even more troubling and remains unresolved. DNA vaccines, by definition, come with the risk of “integration of exogenous DNA into the host genome, which may cause severe mutagenesis and induced new diseases.” Framed in more understandable terms, “disruption from DNA is like inserting a foreign ingredient in an existing recipe, which can change the resulting dish.” The permanent incorporation of synthetic genes into the recipient’s DNA essentially produces a genetically modified human being, with unknown long-term effects. Speaking of DNA gene therapy, one researcher has stated, “Genetic integrations using viral gene therapies . . . can have a devastating effect if the integration was placed in the wrong spot in [the] genome.” Discussing DNA vaccines specifically, the Harvard College Global Health Review elaborates:
    Potential side effects could include chronic inflammation, because the vaccine continuously stimulates the immune system to produce antibodies. Other concerns include the possible integration of plasmid DNA into the body’s host genome, resulting in mutations, problems with DNA replication, triggering of autoimmune responses, and activation of cancer-causing genes.”

  4. NH says:

    Robert F Kennedy Jr. :

    https://articles.mercola.com/sites/articles/archive/2020/05/10/is-there-a-vaccine-for-coronavirus.aspx

    “Kennedy wrote a brilliant foreword to Judy Mikovits’ book “Plague of Corruption,” in which he quotes his father saying, “Moral courage is the rarest species of bravery … rarer than the physical courage of soldiers in battle or great intelligence.” His father believed “moral courage was one of the most vital qualities required to change the world,” Kennedy says.”

    Even after spending 20 years and a couple billion dollars on a dengue fever vaccine you get this:

    https://www.npr.org/sections/goatsandsoda/2019/05/03/719037789/botched-vaccine-launch-has-deadly-repercussions

    “Since the Dengvaxia controversy, the confidence in vaccines among Philippine parents has plummeted from 82% in 2015 to only 21% in 2018, a recent study found. Over that same time span, the proportion of parents who strongly believe vaccines are important has fallen from 93% to 32%.”

  5. Dennis says:

    @NH

    Thanks for those links. The mRNA thing sure looks like one of those ‘What could possibly go wrong?’ ideas.

    Years ago I met some Aussie geneticists who’d come to Sydney for a conference. One talk had really got their attention. It discussed the possibility that a viral infection of proto-humans had effected permanent changes to their DNA consisting of coding repeats for proteins that cause dendritic branching of neutrons with the result being neuronal connections orders of magnitude more complex. Or something like that. I wonder sometimes whether a virus could have a comparable effect on human lifespans and what would happen were it released into the wild.

    Do you remember the Dr Luc Montagnier interview where he said he thought the virus was the result of genetic tinkering?

    https://www.cryptogon.com/?p=58065

    Well, on the first page to which you linked there is a link to another article describing the rapid mutation of the virus:

    https://www.news-medical.net/news/20200422/Coronavirus-has-mutated-into-at-least-30-strains.aspx

    Typically, I would have assumed this was a sign of the virus adapting to its human hosts, but something Montagnier said makes me wonder whether it’s exhibiting instability:

    “Nature does not accept any molecular tinkering, it will eliminate these unnatural changes and even if nothing is done, things will get better, but unfortunately after many deaths.”

    BTW & FWIW, I just found a recent story on how Gates donated $10m to Australian researchers who are examining the potential use of the BCG (tuberculosis) vaccine against coronavirus. You may remember there was a news blip on this topic a while back suggesting those who’d had this vaccination had increased immunity to CV-19 and the possibility that this may have contributed to the much decreased levels of CV-19 infection seen in some countries. I remember lining up in high school in NZ to get ‘scratched’; the vaccine was administered intra-dermally and not via injection.

  6. soothing hex says:

    These ‘new vaccines’ sort of remind me of the exosome theory : https://www.cryptogon.com/?p=57889

  7. NH says:

    Yeah, It struck me as a powerful statement, considering who it was coming from. I’m on the same page as you—that the virus might be exhibiting abnormal instability. There is a link to a follow-up interview a couple weeks later with the Dr Montagnier that has been added to the original interview, which has this additional information:

    “Montagnier also discussed the presence of those HIV segments that are present in the novel coronavirus. He admits although similar segments might be present in other viruses, what remains highly suspicious is that all of these segments are all present in a small section of the coronavirus. Additionaly as the virus is mutating it seems to be mutating in those areas where the HIV segments were added”

    Regarding exosomes/viruses—we have a lot to learn:

    https://www.youtube.com/watch?v=rp4wXSku8Ik&feature=youtu.be

  8. soothing hex says:

    Thanks NH for this video, basically I get the idea is that defensive mechanisms can be triggered by communication channels that include exosomes, allowing to be prepared in advance when a pathogen hits. This can explain both rising asymptomatic ratios and the stop put to the propagation before reaching a 100 % of the population.

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