Psilocybin and Advanced Alzheimer’s Disease
July 13th, 2026A new study found a SINGLE 5g psilocybin dose RESTORED speech, memory, AND bladder control in an advanced Alzheimer’s patient.
After 1 month, the patient was STILL functionally improved and bladder control remained RESTORED.
No Alzheimer’s drug has EVER done anything close. pic.twitter.com/DhmbwMQQom
— Nicolas Hulscher, MPH (@NicHulscher) July 12, 2026
Via: Frontiers in Neuroscience:
We report the case of an octogenarian Japanese-American woman with a 10-year history of Alzheimer’s disease, including 5?years of marked hypofunction and predominantly monosyllabic speech. Baseline features included chronic urinary incontinence, executive dysfunction, dysphagia, dependent mobility, flat affect, and severe reduction in spontaneous communication. The patient received 5 g of orally administered psilocybin-containing mushrooms (Enigma strain). The acute phase was marked by autonomic activation, clinically suspected hyperthermia, profuse sweating, and a prolonged deep sleep-like state. Approximately 19?h post-administration, spontaneous autobiographical speech emerged. Over subsequent days and weeks, functional improvements included restoration of urinary continence, improved ambulation, autonomous dressing, increased emotional responsiveness, sustained social interaction, contextual memory retrieval, preserved working memory for social context, and spontaneous conversational engagement.
