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In March 2008, 168,000 Californians had been out of a job 27 weeks or more — the point where marchunemploymentdurationregular unemployment insurance typically runs out. Last month the number of long-term jobless jumped to 371,000.

The largest group of unemployed in the state is those who have been without jobs five to 14 weeks — 454,000 in March compared to 326,000 a year ago.

Unemployment statewide surged to 11.2% in March, a modern-day record, as the total number of jobless topped 2 million.

Congress has approved three extensions of unemployment insurance in states like California with high unemployment rates. California has the fourth highest rate in the country after Michigan, Oregon and South Carolina.

In the past year, two million people have lost their jobs taking the total out of work to just over four million.

The Bank of Spain recently predicted the jobless rate would reach 19.4% in 2010, as the recession took hold.

“It is a terrible figure,” Octavio Granado, secretary of state for social security told state television.

He said the first quarter of any year was traditionally bad for employment in Spain.

Mr Granado also said that 2009 was expected to be the worst part of the economic downturn.

Staff at US company Merck &Co emailed each other about the list of doctors – mainly researchers and academics – who had been negative about the drug Vioxx or Merck and a recommended course of action.

The email, which came out in the Federal Court in Melbourne yesterday as part of a class action against the drug company, included the words “neutralise”, “neutralised” or “discredit” against some of the doctors’ names.

It is also alleged the company used intimidation tactics against critical researchers, including dropping hints it would stop funding to institutions and claims it interfered with academic appointments.

“We may need to seek them out and destroy them where they live,” a Merck employee wrote, according to an email excerpt read to the court by Julian Burnside QC, acting for the plaintiff.

Merck & Co and its Australian subsidiary, Merck, Sharpe and Dohme, are being sued for compensation by more than 1000 Australians, who claim they suffered heart attacks or strokes as a result of Vioxx.

The drug was launched in 1999 and at its height of popularity was used by 80 million people worldwide because it did not cause stomach problems as did traditional anti-inflammatory drugs.

It was voluntarily withdrawn from sale in 2004 after concerns were raised that it caused heart attacks and strokes and a clinical trial testing these potential side affects was aborted for safety reasons.

Lead plaintiff Graeme Peterson, 58, claims the drug caused him to have a heart attack in 2003 after he took it for back pain and arthritis every day from May 2001.

Merck last year settled thousands of lawsuits in the US over the effects of Vioxx for $US4.85billion ($7.14 billion) but made no admission of guilt.

The company is fighting the class action in Australia.

The Federal Court was told yesterday that Merck wanted to gain the backing of researchers and doctors – or “opinion leaders” – in the fields of arthritis to help promote the drug to medical professionals when it was launched in 1999.

Mr Burnside said internal emails in April 1999 from Merck staff showed the company was not happy with what some researchers and doctors were saying about the drug.

“It gives you the dark side of the use of key opinion leaders and thought leaders … if (they) say things you don’t like to hear, you have to neutralise them,” he said. “It does suggest a certain culture within the organisation about how to deal with your opponents and those who disagree with you.”

The court was told that James Fries, professor of medicine at Stanford University, wrote to the then Merck head Ray Gilmartin in October 2000 to complain about the treatment of some of his researchers who had criticised the drug.

“Even worse were allegations of Merck damage control by intimidation,” he wrote, according to Mr Burnside.

“This has happened to at least eight (clinical) investigators … I suppose I was mildly threatened myself but I never have spoken or written on these issues.”

Mr Burnside told the court Dr Fries went on to describe instances of intimidation, including one colleague who thought his academic appointment had been jeopardised and another who received phone calls alleging “anti-Merck” bias.

Dr Fries said in the letter that Merck had been systematically playing down the side effects of Vioxx and said the company’s behaviour “seriously impinges on academic freedom”. The court was also told a rheumatologist on Merck’s Australian arthritis advisory board was angry he did not find out about Merck’s decision to withdraw Vioxx until an ABC journalist rang to tell him. Mr Burnside said James Bertouch wrote to other members of the board saying he was “extremely disillusioned” with the company.

“In every possible way the company exerted itself to present the impression to the world at large that Vioxx did not provide any increased cardio risk … when (a) it probably would and (b) it probably did,” he wrote, according to Mr Burnside.

Peter Garling, acting for Merck, accused Mr Peterson of not taking the drug Vioxx in the months leading up to his heart attack in December 2003.

He said Pharmaceutical Benefits Scheme figures showed he did not fill a Vioxx prescription for the drug in the two months before his heart attack.

Mr Garling put to Mr Peterson during his cross-examination that this was because he had retired from his job as a safety consultant and therefore he did not need to take Vioxx because his back pain lessened.

Mr Peterson denied this meant he was not taking the drug.

“No, I wouldn’t accept that at all,” he said. “I can remember taking Vioxx regularly.”

Health Secretary Jose Cordova says private and public schools in this metropolis of 20 million have been ordered to remain closed Friday. The measure could be extended in coming days.

Cordova says the flu is a “new, different strain that can attack anyone.” He says authorities are investigating whether it is related to a unique new form of swine flu reported in Texas and California. All seven people in the U.S. recovered.

The government says at least 20 people have died nationwide from the flu in the last three weeks, 13 of them in Mexico City.

None of the seven people were in contact with pigs, which is how people usually catch swine flu. And only a few were in contact with each other, according to the U.S. Centers for Disease Control and Prevention.

Still, health officials said it’s not a cause for public alarm: The five in California and two in Texas have all recovered, and testing indicates some mainstream antiviral medications seem to work against the virus.

Dr. Anne Schuchat of the CDC said officials believe it can spread human-to-human, which is unusual for a swine flu virus.

The CDC is checking people who have been in contact with the seven confirmed cases, who all became ill between late March and mid-April.

Because of intensive searching, it’s likely health officials will find additional cases, said Schuchat, director of the CDC’s National Center for Immunization and Respiratory Diseases.

CDC officials detected a virus with a unique combination of gene segments that have not been seen in people or pigs before. The bug contains human virus, avian virus from North America and pig viruses from North America, Europe and Asia.

Health officials have seen mixes of bird, pig and human virus before, but never such an intercontinental combination with more than one pig virus in the mix.

Scientists keep a close eye on flu viruses that emerge from pigs. The animals are considered particularly susceptible to both avian and human viruses and a likely place where the kind of genetic reassortment can take place that might lead to a new form of pandemic flu, said Dr. John Treanor, an infectious disease specialist at the University of Rochester Medical Center.

The virus may be something completely new, or it may have been around for a while but was only detected now because of improved lab testing and disease surveillance, CDC officials said.

The virus was first detected in two children in southern California — a 10-year-old boy in San Diego County and a 9-year-old girl in neighboring Imperial County.

The cases were detected under unusual circumstances. One was seen at a Navy clinic that participates in a specialized disease detection network, and the other was caught through a specialized surveillance system set up in border communities, CDC officials said.

On Thursday, investigators said they had discovered five more cases. That includes a father and his teenage daughter in San Diego County, a 41-year-old woman in Imperial County (the only person hospitalized), and two 16-year-old boys who are friends and live in Guadalupe County, Texas, near San Antonio.

The Texas cases are especially puzzling. One of the California cases — the 10-year-old boy — traveled to Texas early this month, but that was to Dallas, about 270 miles northeast of San Antonio. He did not travel to the San Antonio area, Schuchat said.

The two 16-year-olds had not traveled recently, Texas health officials said.

The swine flu’s symptoms are like those of the regular flu, mostly involving fever, cough and sore throat, though some of the seven also experienced vomiting and diarrhea.

CDC are not calling it an outbreak, a term that suggests ongoing illnesses. It’s not known if anyone is getting sick from the virus right now, CDC officials said.

It’s also not known if the seasonal flu vaccine that Americans got last fall and early this year protects against this type of virus. People should wash their hands and take other customary precautions, CDC officials said.

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A man in a UAE police uniform is seen on the tape tying the victim’s arms and legs, and later holding him down as the Sheikh pours salt on the man’s wounds and then drives over him with his Mercedes SUV.

In a statement to ABC News, the UAE Ministry of the Interior said it had reviewed the tape and acknowledged the involvement of Sheikh Issa bin Zayed al Nahyan, brother of the country’s crown prince, Sheikh Mohammed.

“The incidents depicted in the video tapes were not part of a pattern of behavior,” the Interior Ministry’s statement declared.

The Minister of the Interior is also one of Sheikh Issa’s brother.

Truck drivers love the birds because they provide better range and sound than ham radios. Rogue loggers in the Amazon use the satellites to transmit coded warnings when authorities threaten to close in. Drug dealers and organized criminal factions use them to coordinate operations.

Today, the satellites, which pirates called “Bolinha” or “little ball,” are a national phenomenon.

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To use the satellite, pirates typically take an ordinary ham radio transmitter, which operates in the 144- to 148-MHZ range, and add a frequency doubler cobbled from coils and a varactor diode. That lets the radio stretch into the lower end of FLTSATCOM’s 292- to 317-MHz uplink range. All the gear can be bought near any truck stop for less than $500. Ads on specialized websites offer to perform the conversion for less than $100. Taught the ropes, even rough electricians can make Bolinha-ware.

The project is being trialled across the six North Wales counties to tackle anti-social behaviour on school buses.

Pupils will use a picture swipe card to clock on and off the bus allowing parents to keep a closer check on their child via a website.

It will help deal with a number of issues including truancy, drivers reporting and identifying ill-behaved children and monitoring a child’s whereabouts in the event of them going missing or a bus breakdown.

The scheme include ‘Bus Angels’ aged 14 and above, who covertly report incidents of bad behaviour,

Peter Daniels, transport manager at Denbighshire County Council said: “The main aims are to support schools, drivers, parents and pupils on school buses to improve behaviour and enable them to understand the consequences of some of the things they do.

“I have to say in north east Wales we don’t really see trouble and misbehaviour, but in the afternoon some of the pupils can be jolly and minor anti-social behaviour can occur, or from time to time something more serious.

“It’s very much like the scheme in London where an Oystercard user boards a bus and taps in and then taps out when he or she gets off.