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“As President Obama indicated during the campaign, there are just a few gun-related changes that we would like to make, and among them would be to reinstitute the ban on the sale of assault weapons,” Holder told reporters.

Holder said that putting the ban back in place would not only be a positive move by the United States, it would help cut down on the flow of guns going across the border into Mexico, which is struggling with heavy violence among drug cartels along the border.

Impolitic or not, Biden’s anxieties seem to have informed several of the administration’s early foreign policy decisions. These include his own extension of an olive branch to Russia at the recent Munich security conference, and Barack Obama’s appointment of Richard Holbrooke as special envoy for Pakistan and Afghanistan – and of George Mitchell to a similar post for Israel-Palestine.

But, as pressing as the Middle East, south Asia, and Russia (as well as Iran and North Korea) are, another crisis far closer to home could create as much peril as a nuclear-armed Iran, an aggressively resurgent Russia, or even an Islamist-dominated Pakistan.

That crisis is located in Mexico, which is in free fall, its state institutions under threat as they have not been since at least the Cristero uprising of the late 1920s and possibly since the Mexican revolution of 1910. While the Obama administration is obviously aware of what is happening south of the Rio Grande, the threat simply does not command the attention that its gravity requires.

The crisis consists in nothing less than an effort by the major drug cartels to tame and suborn the Mexican state, and not just in the strip along the US border, though the epicentre of the crisis is there. Obviously, the cartels’ leaders do not have designs on Mexico’s presidential palace. But, through a policy of terror extending from Oaxaca in the south, through Acapulco on the Pacific coast, and up to the great border cities of Tijuana and Juarez (Mexico’s sixth and seventh most populous cities, respectively), they have made it abundantly clear that they are trying to achieve impunity.

The only recent parallel in Latin America was a similar effort 15 years ago by the Colombian drug cartels. That disguised coup failed – barely – and there is no guarantee that the result will be similar this time around in Mexico.

Journalists with long experience of war zones report being more worried about their safety in Mexico border than when they were in Bosnia, Afghanistan, or Iraq, though much of the violence is internecine. Of the thousands who have been killed, often after being horribly tortured, many, if not most, have been members of the drug cartels and their families.

But it is the campaign of targeted assassination against any Mexican official who seems to pose a serious threat to the cartels’ operations that makes the crisis so dire. First, in May 2007, the cartels killed Jose Nemesio Lugo Felix, the general co-ordinator of information at the national centre for planning and analysis to combat organised crime. Soon after, a hitman murdered Edgar Milan Gomez, Mexico’s highest ranking federal police official.

The arrests, including 50 on Wednesday in California, Minnesota, Maryland and the nation’s capital, come amid growing concern in Washington that Mexican crime organizations are out of control and threaten the stability of parts of Mexico and the safety of U.S. citizens.

The Homeland Security Department has developed a plan to send more agents and other resources, and possibly military support, to the U.S.-Mexico border if the drug violence continues to spill over and overwhelm the agents stationed there, a department official confirmed.

The Pentagon is looking into a larger role in bolstering counter-narcotics efforts. Adm. Dennis C. Blair, the director of national intelligence, told Congress on Wednesday that the corruptive influence and increasing violence of the cartels had undermined the Mexican government’s ability to govern parts of its country.

A recent State Department travel advisory warned U.S. citizens about the perils of travel in Mexico, likening the shootouts between authorities and the cartels to “small-unit combat.” The U.S. National Drug Intelligence Center believes that Mexican cartels maintain drug distribution networks or supply drugs to distributors in as many as 195 U.S. cities.

And on Wednesday, Rep. Lamar Smith (R-Texas), the ranking member of the House Judiciary Committee, said the recent surge in drug-related violence on the Southwest border “has turned some American communities and neighborhoods into the Wild West.”

CIA Director Leon Panetta, in his first meeting with reporters, said the agency will continue to carry out drone attacks on militants in Pakistan. He also said that while CIA interrogations will have new limits, President Barack Obama can still use his wartime powers to authorize harsher techniques if necessary.

Among changes under way at the CIA, the agency is now assembling a daily Economic Intelligence Brief to monitor the global economic slowdown’s impact on stability. Argentina, Ecuador and Venezuela are facing “serious problems” that threaten their economic stability, Mr. Panetta said.

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That company, Avir Green Hills Biotechnology, then disseminated the supposed H3N2 virus product to subcontractors in the Czech Republic, Slovenia and Germany. Authorities in the four European countries are looking into the incident, and their efforts are being closely watched by the World Health Organization and the European Centre for Disease Control.

Though it appears none of the 36 or 37 people who were exposed to the contaminated product became infected, the incident is being described as “a serious error” on the part of Baxter, which is on the brink of securing a European licence for an H5N1 vaccine. That vaccine is made at a different facility, in the Czech Republic.

“For this particular incident … the horse did not get out (of the barn),” Dr. Angus Nicoll of the ECDC said from Stockholm.

“But that doesn’t mean that we and WHO and the European Commission and the others aren’t taking it as seriously as you would any laboratory accident with dangerous pathogens – which you have here.”

Accidental release of a mixture of live H5N1 and H3N2 viruses – if that indeed happened – could have resulted in dire consequences. Nicoll said officials still aren’t 100 per cent sure the mixture contained live H5N1 viruses. But given that ferrets exposed to the mixture died, it likely did.

H5N1 doesn’t easily infect people, but H3N2 viruses do. They are one of two types of influenza A viruses that infect people each flu season.

If someone exposed to the mixture had been co-infected with H5N1 and H3N2, the person could have served as an incubator for a hybrid virus able to transmit easily to and among people. That mixing process, called reassortment, is one of two ways pandemic viruses are created.

Research published last summer by scientists at the U.S. Centers for Disease Control found that in the laboratory, H5N1 and H3N2 viruses mated readily. While less virulent than H5N1, a number of the offspring viruses appeared to retain at least a portion of the killing power of their dangerous parent.

Baxter International, which is based in Deerfield, Ill., said the contamination was the result of an error in its research facility in Orth-Donau, Austria.

The facility had been contracted by Avir Green Hills to make what Baxter refers to as “experimental virus material” based on human H3N2 viruses.

Christopher Bona, Baxter’s director of global bioscience communications, said the liquid virus product was not a vaccine and was developed for testing purposes only. He deferred questions about the purpose of the testing to Avir Green Hills, but said the batch was to be used in animals and was never intended for use in humans.

Avir Green Hills said in an email that it took possession of the material in late December. It later sent the product to the sub-contractors. The email said the material was stored and handled throughout under high biosafety conditions.

Alarm bells rang in early February when researchers at the Czech sub-contractor inoculated ferrets with the material and the animals promptly died. Baxter learned about the problem on Feb. 6, Bona said from Deerfield.

Ferrets are susceptible to human flu strains, but they don’t die from those infections. Preliminary investigation found the material was contaminated with H5N1 flu virus, which is lethal to ferrets.

Nicoll said the fact the ferrets died supports the working assumption that there were live H5N1 viruses in the material Baxter produced.

Bona said Baxter has identified how the contamination happened and has taken steps to ensure it doesn’t happen again. He said Austrian authorities audited Baxter’s Orth-Donau research operations after the problem came to light and are satisfied with the steps taken.

Baxter is the only flu vaccine manufacturer to work with wild type flu viruses, felt to be more dangerous than the altered and attenuated (weakened) viruses other manufacturers use.

The company uses what is known as BSL3 level precautions in all its vaccine research facilities, Bona said. (Researchers at the U.S. CDC use BSL3-plus biocontainment when working with H5N1 viruses, a spokesperson for the agency said.)

People familiar with biosecurity rules are dismayed by evidence that human H3N2 and avian H5N1 viruses have somehow co-mingled in the Baxter research facility. That should not be allowed to happen, a number of experts insisted.

The company isn’t shedding much light on how it did.

“It was a combination of just the process itself, (and) technical and human error in this procedure,” Bona said. When asked to elaborate, he said to do so would give away proprietary information about Baxter’s production process.

Bona said when Baxter realized its error, it helped the various companies destroy the contaminated material and clean up their facilities. And staff who had been exposed to the contaminated product were assessed and monitored by infectious diseases doctors. They were also offered the antiviral drug oseltamivir (Tamiflu).

Baxter’s error is reminiscent of a 2005 incident where a U.S. manufacturer of kits used by laboratories to test their detection capabilities included vials of H2N2 virus in several thousand proficiency kits. H2N2, the virus that caused the 1957 pandemic, has not circulated since 1968 and is thought to be a prime candidate to cause the next pandemic.

And an official of the World Health Organization’s European operation said the body is closely monitoring the investigation into the events that took place at Baxter International’s research facility in Orth-Donau, Austria.

“At this juncture we are confident in saying that public health and occupational risk is minimal at present,” medical officer Roberta Andraghetti said from Copenhagen, Denmark.

“But what remains unanswered are the circumstances surrounding the incident in the Baxter facility in Orth-Donau.”

The contaminated product, a mix of H3N2 seasonal flu viruses and unlabelled H5N1 viruses, was supplied to an Austrian research company. The Austrian firm, Avir Green Hills Biotechnology, then sent portions of it to sub-contractors in the Czech Republic, Slovenia and Germany.

The contamination incident, which is being investigated by the four European countries, came to light when the subcontractor in the Czech Republic inoculated ferrets with the product and they died. Ferrets shouldn’t die from exposure to human H3N2 flu viruses.

Public health authorities concerned about what has been described as a “serious error” on Baxter’s part have assumed the death of the ferrets meant the H5N1 virus in the product was live. But the company, Baxter International Inc., has been parsimonious about the amount of information it has released about the event.

On Friday, the company’s director of global bioscience communications confirmed what scientists have suspected.

“It was live,” Christopher Bona said in an email.

The contaminated product, which Baxter calls “experimental virus material,” was made at the Orth-Donau research facility. Baxter makes its flu vaccine — including a human H5N1 vaccine for which a licence is expected shortly — at a facility in the Czech Republic.

People familiar with biosecurity rules are dismayed by evidence that human H3N2 and avian H5N1 viruses somehow co-mingled in the Orth-Donau facility. That is a dangerous practice that should not be allowed to happen, a number of experts insisted.

Accidental release of a mixture of live H5N1 and H3N2 viruses could have resulted in dire consequences.

While H5N1 doesn’t easily infect people, H3N2 viruses do. If someone exposed to a mixture of the two had been simultaneously infected with both strains, he or she could have served as an incubator for a hybrid virus able to transmit easily to and among people.

That mixing process, called reassortment, is one of two ways pandemic viruses are created.

There is no suggestion that happened because of this accident, however.

“We have no evidence of any reassortment, that any reassortment may have occurred,” said Andraghetti.

“And we have no evidence of any increased transmissibility of the viruses that were involved in the experiment with the ferrets in the Czech Republic.”

Baxter hasn’t shed much light — at least not publicly — on how the accident happened. Earlier this week Bona called the mistake the result of a combination of “just the process itself, (and) technical and human error in this procedure.”

He said he couldn’t reveal more information because it would give away proprietary information about Baxter’s production process.

Andraghetti said Friday the four investigating governments are co-operating closely with the WHO and the European Centre for Disease Control in Stockholm, Sweden.

“We are in very close contact with Austrian authorities to understand what the circumstances of the incident in their laboratory were,” she said.

The shortfall widened to 952.6 billion yen ($9.9 billion), the biggest since 1980, the earliest year for which there is comparable data, the Finance Ministry said today in Tokyo. The drop in shipments abroad eclipsed a record 35 percent decline set the previous month.

What do you think of him?
I’ll make a general comment about this whole dependence on “celebrities.” I object to this situation as it is right now where they have inadvertently or manipulatively become the spokespeople for the African continent.

You argue in your book that Western aid to Africa has not only perpetuated poverty but also worsened it, and you are perhaps the first African to request in book form that all development aid be halted within five years.
Think about it this way — China has 1.3 billion people, only 300 million of whom live like us, if you will, with Western living standards. There are a billion Chinese who are living in substandard conditions. Do you know anybody who feels sorry for China? Nobody.

Maybe that’s because they have so much money that we here in the U.S. are begging the Chinese for loans.
Forty years ago, China was poorer than many African countries. Yes, they have money today, but where did that money come from? They built that, they worked very hard to create a situation where they are not dependent on aid.

What do you think has held back Africans?
I believe it’s largely aid. You get the corruption — historically, leaders have stolen the money without penalty — and you get the dependency, which kills entrepreneurship. You also disenfranchise African citizens, because the government is beholden to foreign donors and not accountable to its people.

Mohammed Gul, 20, is accused of two counts of transmitting a terrorist publication in January this year.

He is also charged with owning a document containing information likely to be useful to a person committing or preparing an act of terrorism.

Mr Gul, who lives in Elm Park Avenue, Hornchurch, east London was charged with the offences late on Monday evening.

He was arrested by anti-terror police officers on February 10 at an address in Hornchurch, a Metropolitan Police spokesman said.

The force would not reveal details of the document allegedly found in Mr Gul’s possession.

That’s just one of the findings of a report released on Monday by Energy Department Inspector General Gregory Friedman that concluded “the department cannot properly account for and effectively manage its nuclear materials maintained by domestic licensees and may be unable to detect lost or stolen material.”

Auditors found that Energy could not accurately account for the quantities and locations of nuclear material at 15 out of 40, or 37 percent, of facilities reviewed. The materials written off included 20,580 grams of enriched uranium, 45 grams of plutonium, 5,001 kilograms of normal uranium and 189,139 kilograms of depleted uranium.

“Considering the potential health risks associated with these materials and the potential for misuse should they fall into the wrong hands, the quantities written off were significant,” the report stated. “Even in small quantities normally held by individual domestic licensees, special nuclear materials such as enriched uranium and plutonium, if not properly handled, potentially pose serious health hazards.”

Auditors also found that waste processing facilities could not locate or explain the whereabouts of significant quantities of uranium and other nuclear material that Energy Department records showed they held. In another case, Energy officials had no record of the fact that one academic institution had loaned a 32-gram plutonium-beryllium source to another institution.

The audit was a follow-up to a 2001 probe that found similar record-keeping problems. “Key commitments made by the department were not completed nearly eight years after our earlier audit,” Friedman reported.

More than 100 academic and commercial institutions and government agencies lease nuclear materials that are owned by Energy. The department, along with the Nuclear Regulatory Commission, is supposed to track these materials through the centralized accounting system known as the Nuclear Materials Management and Safeguards System, or NMMSS.

“Due to the inconsistencies documented in our report, it would be extremely difficult, if not impossible, for the department to accurately identify the type and quantity of its nuclear materials affected if an incident occurred at one of the sites whose NMMSS inventory we could not verify,” the IG stated in Monday’s report.

The $50 million fund was jointly branded between the Bidens’ Paradigm Global Advisors and a Stanford Financial Group entity, and was known as the Paradigm Stanford Capital Management Core Alternative Fund, the paper said.

Stanford-related companies marketed the fund to investors and also invested about $2.7 million of their own money in the fund, the paper said, citing a lawyer for Paradigm.

Paradigm Global Advisors is owned through a holding company by the vice president’s son, Hunter, and Joe Biden’s brother, James, according to the paper.

Paradigm’s attorney, Marc LoPresti, who represents Hunter Biden and James Biden, as well as Paradigm, told the paper he did not know which Stanford entity invested the roughly $2.7 million.

He told the paper the Bidens never met or communicated with Stanford.

Joe Biden’s office and the U.S. Securities and Exchange Commission (SEC) could not be immediately reached for comment by Reuters.

The paper cited LoPresti as saying the fund offered to turn over the $2.7 million investment it received from Stanford’s firm in 2007 to a court-appointed receiver in the SEC’s civil fraud case involving Stanford.