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A former U.S. government source with knowledge of the BBG says the organization is no Pravda, but it does advance U.S. interests in more subtle ways. In Somalia, for instance, VOA serves as counterprogramming to outlets peddling anti-American or jihadist sentiment. “Somalis have three options for news,” the source said, “word of mouth, Al-Shabaab or VOA Somalia.”

The meeting was convened, as always, by the American Medical Association. Since 1992, the AMA has summoned this same committee three times a year. It’s called the Specialty Society Relative Value Scale Update Committee (or RUC, pronounced “ruck”), and it’s probably one of the most powerful committees in America that you’ve never heard of.

The purpose of each of these triannual RUC meetings is always the same: it’s the committee members’ job to decide what Medicare should pay them and their colleagues for the medical procedures they perform. How much should radiologists get for administering an MRI? How much should cardiologists be paid for inserting a heart stent?

While these doctors always discuss the “value” of each procedure in terms of the amount of time, work, and overhead required of them to perform it, the implication of that “value” is not lost on anyone in the room: they are, essentially, haggling over what their own salaries should be. “No one ever says the word ‘price,’ ” a doctor on the committee told me after the April meeting. “But yeah, everyone knows we’re talking about money.”

That doctor spoke to me on condition of anonymity in part because all the committee members, as well as more than a hundred or so of their advisers and consultants, are required before each meeting to sign what was described to me as a “draconian” nondisclosure agreement. They are not allowed to talk about the specifics of what is discussed, and they are not allowed to remove any of the literature handed out behind those double doors. Neither the minutes nor the surveys they use to arrive at their decisions are ever published, and the meetings, which last about five days each time, are always closed to both the public and the press. After that meeting in April, there was not so much as a single headline, not in any major newspaper, not even on the wonkiest of the TV shows, announcing that it had taken place at all.

In a free market society, there’s a name for this kind of thing—for when a roomful of professionals from the same trade meet behind closed doors to agree on how much their services should be worth. It’s called price-fixing. And in any other industry, it’s illegal—grounds for a federal investigation into antitrust abuse, at the least.

The technology is based on the “T-cell receptor”, the protein that sticks out of the surface of the T-cell and binds to its enemy target. Immunocore’s ImmTACs are effectively independent T-cell receptors that are “bispecific”, meaning they bind strongly to cancer cells at one end, and T-cells at the other – so introducing cancer cells to their nemesis.

“What we can do is to use that scaffold of the T-cell receptor to make something that is very good at recognising cancer even if it doesn’t exist naturally,” said Dr Jakobsen. “Although T-cells are not very keen at recognising cancer, we can force them to do so. The potential you have if you can engineer T-cell receptors is quite enormous. You can find any type of cell and any kind of target. This means the approach can in theory be used against any cancer, whether it is tumours of the prostate, breast, liver or the pancreas.

The key to the success of the technique is being able to distinguish between a cancer cell and a normal, healthy cell. Immunocore’s drug does this by recognising small proteins or peptides that stick out from the surface membrane of cancer cells. All cells extrude peptides on their membranes and these peptides act like a shop window, telling scientists what is going on within the cell, and whether it is cancerous or not.

“All these little peptides tell you the story of the cell. The forest of them on the cell surface is a sort of display saying ‘I am this kind of cell. This is my identity and this is everything going on inside me’,” Dr Jakobsen explained.

Immunocore is building up a database of peptide targets on cancer cells in order to design T-cell receptors that can target them, leaving healthy cells alone and so minimising possible side effects – or that is the hope.

hacking the CA
social engineering (install the certificate)
relying on click-through syndrome for SSL warnings

The for-profit detention center, surrounded by razor wire and near the forests and farms of central Mississippi, had 27 assaults per 100 offenders last year, more than any other prison in the state, according to an April court filing. Staff shortages, mismanagement and lax oversight had long turned it into a cauldron of violence, where female employees had sex with inmates, pitted them against each other, gave them weapons and joined their gangs, according to court records, interviews and a U.S. Justice Department report.

“It was like a jungle,” said Craig Kincaid, 24, a former inmate. “It was an awful place to go when you’re trying to get your life together.”

More than 130,000 state and federal convicts throughout the U.S. — 8 percent of the total — now live in private prisons such as Walnut Grove, as public officials buy into claims that the institutions can deliver profits while preparing inmates for life after release, saving tax dollars and creating jobs.

Kirk Merricks, 43, of Dorchester, was charged Friday with 11 counts of possession of explosives, along with theft and ammunition charges.

Police say they received a call on Thursday from the homeowner, identified as Merricks’ estranged wife, saying she was cleaning out a bedroom closet and found four ¼ sticks of TNT and assorted ammunition in a metal box marked “highly explosive.”

The bomb squad responded to the home on Paddington Way, where explosives experts recovered a briefcase from a shed outside the home that had “a bandolier that contained four military-grade M203 rounds, six detonator cords with attached blasting caps and two rolls of timed fused cord connected to non-electric fixing mechanisms,” District Attorney’s office reported.

A 486,540-rouble (£9,860) order for electric typewriters has been placed by the FSO agency on the state procurement website.

The FSO has not commented on why it needs the old-fashioned devices.

But an agency source told Russia’s Izvestiya newspaper the aim was to prevent leaks from computer hardware.

“After scandals with the distribution of secret documents by WikiLeaks, the exposes by Edward Snowden, reports about Dmitry Medvedev being bugged during his visit to the G20 London summit (in 2009), it has been decided to expand the practice of creating paper documents,” the source said.

The source added that typewriters were already being used at Russia’s defence and emergencies ministries for drafts and secret notes, and some reports had been prepared for President Vladimir Putin by typewriter.

The announcement is in stark contrast to the pronouncement last week by health officials in the United States that vaccination rates in teenage girls should be increased after a study concluded that estimated vaccine effectiveness is “high.”

The Japanese Ministry of Health, Labor, and Welfare is not suspending vaccination, but has instructed local governments not to promote the use of the medicine while analyses are conducted about adverse effects, such as long-term pain and numbness, according to the Japanese newspaper The Asahi Shimbun.

“The decision does not mean that the vaccine itself is problematic from the viewpoint of safety,” said Mariko Momoi, who heads a ministry task force looking into the controversy and is a vice president of the International University of Health and Welfare in O-tawara, Tochigi, Japan. “By implementing investigations, we want to offer information that can make the people feel more at ease.”

ATLAS was developed for DARPA by Boston Dynamics. Software-focused teams from Tracks B and C of the DARPA Robotics Challenge will use the robot to compete in the first physical competition of the Challenge in December 2013 at the Homestead-Miami Speedway.

The DARPA Robotics Challenge seeks to advance the technology necessary to create robots capable of assisting humans in disaster response.

“I am pleased to announce that the Special Committee has nominated Secretary of Homeland Security Janet Napolitano to serve as the 20th president of the University of California,” UC Regent and Committee Chair Sherry Lansing said.